Weight loss injections have gained huge popularity in recent years — but do they actually work? Are they safe? And how do they compare to more traditional weight loss methods like pills or dieting alone?
In this article, we’ll explore the science behind weight loss injections, who they’re for, and what kind of results you can realistically expect.
Lose up to 26% body weight
Free, fast and discreet delivery
12,255 reviews and counting
Written by
Rob Farrow
Reviewed by
Medicspot Staff Author
Author
Last Updated:
Next Review: Jul 31, 2027
Firstly let’s just cover the basic info about weight loss injections (you can skip this bit if you already know it and move on to the information about whether they work.)
Weight loss injections are prescription medications that are delivered via a subcutaneous (under the skin) injection — usually once per week.
Most are GLP-1 receptor agonists. These medications mimic a hormone that helps regulate appetite and blood sugar.
Common brands include:
Mounjaro (tirzepatide) – dual GIP/GLP-1 receptor agonist
Wegovy (semaglutide) – weekly GLP-1 injection
Saxenda (liraglutide) – daily GLP-1 injection
How Do They Work? GLP-1 weight loss injections:
Reduce appetite and cravings
Slow the emptying of your stomach
Help you feel fuller for longer
Improve blood sugar control (especially useful in people with type 2 diabetes)
Over time, this leads to reduced calorie intake and consistent, sustainable weight loss — especially when combined with lifestyle changes.
Yes. Multiple clinical trials and real-world patient data show that GLP-1 injections can lead to significant weight loss.
Mounjaro can facilitate 26% weight loss over 18 months.
Wegovy can typically help patients lose 15%.
Saxenda results are normally around 10% weight loss.
Weight loss injections are typically prescribed for people who:
Have a BMI of 30 or higher, or 27+ with a related health condition (e.g. PCOS, high blood pressure, type 2 diabetes)
Have tried to lose weight through lifestyle changes without success
Are willing to follow a long-term medical plan that includes dietary changes and physical activity
Take our Free Online Assessment now to find out if you are eligible.
Everyone is different, A typical patient journey might look something like this:
Month 1 – reduced cravings, small weight drop
Months 2-3 – steady weight loss, improved energy
Months 4-6 – noticeable changes in body shape and appetite control
Compared to pills (like Orlistat) or dieting without medical support, injections generally offer:
Greater average weight loss
Improved blood sugar and insulin regulation
Better appetite control
Higher adherence (thanks to fewer food cravings)
Ready to take the next step? Take our Free Online Assessment (no appointment needed; no need to speak to a Doctor)
Do you have more questions? Would you like to speak with someone? Book a free call with our team.
